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Celine Sze Ling CHUI
ORCID

Dr. Chui is jointly appointed by the School of Nursing and School of Public Health at HKU. She obtained her PhD degree from the Department of Pharmacology and Pharmacy at HKU in 2017. She had led the design and analysis of studies using electronic health records from multi-databases (including Hong Kong, Taiwan, United Kingdom, Sweden, and Australia). She was a visiting scholar (PhD exchange student) at the London School of Hygiene and Tropical Medicines in United Kingdom. She completed her post-doctoral training in the School of Public Health at HKU in 2019.

Dr Chui aims to utilize Big Data from multi-regional/national large healthcare databases and that collected in the community to improve public health. Her current research focuses on cardiovascular disease risk prediction and evaluation using artificial intelligence (AI), Big Data for antimicrobial resistance surveillance, and improving care of people living with dementia. Dr Chui is a Co-principal investigator of AI and Pharmaceuticals in Non-Communicable Diseases at the Laboratory of Data Discovery for Health (D²4H). Dr Chui is also the convener and active member of NeuroGEN (Neurological and Mental Health Global Epidemiology Network), and one of the lead researchers in the CARE Programme, a comprehensive surveillance programme to monitor known and potential adverse events of COVID-19 vaccines.

She is the Principal investigator of a cardiovascular risk prediction model designed for Hong Kong population - P-CARDIAC (Personalised - CARdiovascular DIsease risk Assessment for Chinese) which her work is extensively covered by the media. Dr Chui has an h-index (Scopus) of 21 and has published more than 80 articles in peer-reviewed journals such as The Lancet Infectious Disease, Annals of Internal Medicine, BMJ, JAMA Internal Medicine, and Journal of the American College of Cardiology.

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Co-principal investigator or research lead*

Funding Scheme Project Title Approved Amount (HK$)
Research Grant Council (RGC) Early Career Scheme Safe Antibiotics use in the Management of PEople with Dementia (SAMPED) 921,882
Food and Health Bureau, The Government of the Hong Kong Special Administrative Region COVID-19 vaccines Adverse events Response and Evaluation (CARE) Programme* 10,000,000
RGC Collaborative Research Fund (CRF) Coronavirus Disease (COVID-19) and Novel Infectious Disease (NID) Research Exercise* A multinational big data Covid-19 Epidemiological Study on post-infection Outcomes (ACESO) 9,691,060
Innovation and Technology Fund, Partnership Research Programme Cardiovascular risk prediction model for patients on lipid modifying drugs 3,047,842
Research Grant Council (RGC) General Research Fund Association between the use of different classes of blood pressure-lowering drugs and risk of incident dementia: a multidatabase study 694,305
Health and Medical Research Fund (HMRF) Commissioned Paediatric Research at Hong Kong Children’s Hospital* Epidemiology and effect of antibiotic exposure on antimicrobial resistance bacterial carriages and gut microbiota among children and their caregivers in the Hong Kong Children’s Hospital* 1,544,933

Co-first author*

  1. Chui CSL, Cheung KS, Brown JP, Douglas IJ, Wong ICK, Chan EW, Wong AYS. Proton pump inhibitors and myocardial infarction: an application of active comparators in a self-controlled case series. International Journal of Epidemiology. 2022 Oct 19:dyac196. Available from: doi: 10.1093/ije/dyac196.
  2. Wan EYF*, Chui CSL*, Ng VWS, Wang Y, Yan VKC, Lam ICH, Fan M, Lai FTT, Chan EWY, Li X, Wong CKH, Chung RKC, Cowling BJ, Fong WC, Lau AYL, Mok VCT, Chan FLF, Lee CK, Chan LST, Lo D, Lau KK, Hung IFN, Lau CS, Leung GM, Wong ICK. mRNA (BNT162b2) COVID-19 vaccination increased risk of Bell's palsy: a nested case control and self-controlled case series study. Clinical Infectious Diseases. 2022 Jun 8:ciac460. Available from: doi: 10.1093/cid/ciac460.
  3. Chui CSL*, Fan M*, Wan EYF, Leung MTY, Cheung E, Yan VKC, Gao L,  Ghebremichael-Weldeselassie Y, Man KKC, Lau KK, Lam ICH, Lai FTT, Li X, Wong CKH, Chan EW, Cheung CL, Sing CW, Lee CK, Hung IFN, Lau CS, Chan JYS, Lee MKY, Mok VCT, Siu CW, Chan LST, Cheung T, Chan FLF, Leung AYH, Cowling BJ, Leung GM, Wong ICK. Thromboembolic events and hemorrhagic stroke after mRNA (BNT162b2) and inactivated (CoronaVac) covid-19 vaccination: a self-controlled case series study. EClinicalMedicine. 2022 Jun 25;50:101504. Available from: doi: 10.1016/j.eclinm.2022.101504.
  4. Wan EYF*, Chui CSL*, Lai FTT, Chan EWY, Li X, Yan VKC, Gao L, Yu Q., Lam ICH, Chun RKC, Cowling BJ, Fong WC, Lau AYL, Mok VCT, Chan FLF, Lee CK, Chan LST, Lo D, Lau KK, Hung IFN, Leung GM, Wong ICK. Bell's palsy following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines: a case series and nested case-control study. The Lancet. Infectious Diseases, S1473-3099(21)00451-5.
  5. Chui CSL*, Wan EYF*, Wang Y, Ng VWS, Yan VKC, Lai FTT, Li X, Wong CKH, Chan EWY, Wong CSM, Leung KSM, Ni MY, Valkenburg SA, Peiris JSM, Wu JTK, Cowling BJ, Ashcroft DM, Hung IFN, Leung GM, Wong ICK. Herpes zoster related hospitalization after inactivated (CoronaVac) and mRNA (BNT162b2) SARS-CoV-2 vaccination: A self-controlled case series and nested case-control study. The Lancet Regional Health-Western Pacific. 2022 Apr;21:100393. doi: 10.1016/j.lanwpc.2022.100393.
  6. Chui CS, Cowling BJ, Lim WW, Hui CK, Chan EW, Wong IC, Wu P. Patterns of inpatient antibiotic use among public hospitals in Hong Kong from 2000 to 2015. Drug safety. 2020 Mar 12; 43(6):595‐606.
  7. Chui CS, Chan EW, Wong AY, Root A, Douglas IJ, Wong IC. Association between oral fluoroquinolones and seizures: a self-controlled case series study. Neurology. 2016 April 6;86(18):1708-15.
  8. Wong AY, Wong IC, Chui CS, Lee EH, Chang WC, Chen EY, Leung WK, Chan EW. Association between acute neuropsychiatric events and Helicobacter pylori therapy containing clarithromycin. JAMA internal medicine. 2016 May 2;176(6):828-34. Available from: doi: 10.1001/jamainternmed.2016.1586
  9. Chui CS, Wong IC, Wong LY, Chan EW. Association between oral fluoroquinolone use and the development of retinal detachment: a systematic review and meta-analysis of observational studies. Journal of Antimicrobial Chemotherapy. 2015 Apr;70(4):971-8.
  10. Chui CS, Man KK, Cheng CL, Chan EW, Lau WC, Cheng VC, Wong DS, Yang Kao YH, Wong IC. An investigation of the potential association between retinal detachment and oral fluoroquinolones: a self-controlled case series study. Journal of Antimicrobial Chemotherapy. 2014 Sep;69(9):2563-7.
Since 2022 Editorial Board Member, Scientific Reports

The Lancet, JAMA Network Open, Psychological Medicine, British Journal of Clinical Pharmacology, PLoS One, Journal of Antimicrobial Chemotherapy, Hong Kong Journal of Paediatrics, BMC Musculoskeletal Disorder, Scientific Reports

Since 2022 Steering Committee Member, The Observational Health Data Sciences and Informatics (OHDSI) Asia-Pacific Community (APAC)
2021/03- current Honorary Advisor in Quality and Safety Division of Hospital Authority Head Office (HAHO), Hong Kong Government
2019/11-current Honorary Research Fellow, UCL School of Pharmacy, London, United Kingdom
2019/02-current Honorary Research Assistant, Department of Pharmacy, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China
2018/01-current Member, The University of Hong Kong Shenzhen Institute of Research and Innovation, Shenzhen, China
2018-current Convener and active member NeuroGEN (Neurological and Mental Health Global Epidemiology Network)
2015-16 Chair, Student Council, International Society for Pharmacoepidemiology
2014-15 Co-chair, Student Council, International Society for Pharmacoepidemiology
  • Outstanding Research Output Award, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 2022
  • ASM Student and Postdoctoral Travel Award, ASM (American Society for Mcirobiology) Microbe, 2018
  • Outstanding Research Output Award, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 2017
  • John Snow Award (Best abstract submitted from a female research or a student living in a developing country), 32nd ICPE International Conference on Pharmacoepidemiology & Therapeutic Risk Management, 2016
  • Roche Postgrduate Research Student Prize, The University of Hong Kong, 2015
  • Rising Start Award, 9th Asian Conference on Pharmacoepidemiology, 2015
  • First Poster Prize, 14th Annual Meeting of the International Society of Pharmacovigilance, 2014
  • Best Presenter Award in Cardiovascular Issues and Antibiotics, 8th Asian Conference on Pharmacoepidemiology, 2013
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