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Celine Sze Ling CHUI
ORCID

Dr. Chui is jointly appointed by the School of Nursing and School of Public Health at HKU. She obtained her PhD degree from the Department of Pharmacology and Pharmacy at HKU in 2017. Her PhD work focused on the safety of oral fluoroquinolones using multi-databases. She had led the design and analysis of several studies using healthcare databases from Hong Kong, Taiwan, and the United Kingdom. She was a visiting scholar (PhD exchange student) at the London School of Hygiene and Tropical Medicines in United Kingdom. She completed her post-doctoral training in the School of Public Health at HKU in 2019.

Dr Chui aims to utilize Big Data from multi-regional/national large healthcare databases and that collected in the community to improve public health. Her current research focuses on cardiovascular disease risk prediction and evaluation using artificial intelligence (AI), Big Data for antimicrobial resistance, and improving care of people living with dementia. Dr Chui is a Co-principal investigator of AI and Pharmaceuticals in Non-Communicable Diseases at the Laboratory of Data Discovery for Health (D²4H). Dr Chui is also the convener and active member of NeuroGEN (Neurological and Mental Health Global Epidemiology Network), and one of the lead researchers in the CARE Programme, a comprehensive surveillance programme to monitor known and potential adverse events of COVID-19 vaccines. She is the principal investigator or co-principal investigator of grants funded by Innovation and Technology Fund, Research Grant Council, and Health and Medical Research Fund. Dr Chui has published more than 30 articles in peer-reviewed journals such as The Lancet Infectious Disease, JAMA Internal Medicine, BMJ, Journal of the American College of Cardiology, and Neurology.

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Co-principal investigator or research lead*

Funding Scheme Project Title Approved Amount (HK$)
IQVIA Burden of pneumococcal disease in children and adults in selected Asia-Pacific countries – A retrospective database study 750,000
Enhanced New Staff Start-up Research Grant, The University of Hong Kong, LKS Faculty of Medicine Polypharmacy and its impacts on adverse outcomes in senior people with dementia in Hong Kong and Australia-A population-based study 380,000
Food and Health Bureau, The Government of the Hong Kong Special Administrative Region COVID-19 vaccines Adverse events Response and Evaluation (CARE) Programme* 10,000,000
RGC Collaborative Research Fund (CRF) Coronavirus Disease (COVID-19) and Novel Infectious Disease (NID) Research Exercise* A multinational big data Covid-19 Epidemiological Study on post-infection Outcomes (ACESO) 9,691,060
Innovation and Technology Fund, Partnership Research Programme Cardiovascular risk prediction model for patients on lipid modifying drugs 3,047,842
Research Grant Council (RGC) General Research Fund Association between the use of different classes of blood pressure-lowering drugs and risk of incident dementia: a multidatabase study 694,305
Health and Medical Research Fund (HMRF) Commissioned Paediatric Research at Hong Kong Children’s Hospital* Epidemiology and effect of antibiotic exposure on antimicrobial resistance bacterial carriages and gut microbiota among children and their caregivers in the Hong Kong Children’s Hospital 1,544,933
Pfizer Understand the epidemiology of Carbapenemase-producing Enterobacteriaceae and Multi-drug/Extensively-drug resistant Pseudomonas aeruginosa cases in Hong Kong 481,997
Seed Fund for Basic Research for New Staff, The University of Hong Kong, LKS Faculty of Medicine Disease and treatment burden of Motor Neuron Disease: with the use of big data platform (NeuroGEN) in Hong Kong. 150,000
  • Epidemiology with the use of Big Data
  • Methodological research
  • Medication safety and drug utilization
  1. Wan EYF, Chui CSL#, Lai FTT, Chan EWY, Li X, Yan VKC, Gao L, Yu Q, Lam ICH, Chun RKC, Cowling BJ, Fong WC, Lau AYL, Mok VCT, Chan FLF, Lee CK, Chan LST, Lo D, Lau KK, Hung IFN, Leung GM, Wong ICK. Bell's palsy following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines: a case series and nested case-control study. The Lancet Infectious Diseases. 2022 Jan;22(1):64-72. Available from: doi: 10.1016/S1473-3099(21)00451-5
  2. Ju C, Wong ICK, Lau WCY, Man KKC, Brauer R, Ma TT, Alsharif A, Alwafi H, Lau KK, Chan EW, Chui CSL, Li X, Wei L. Global trends in symptomatic medication use against dementia in 66 countries/regions from 2008 to 2018. European Journal of Neurology. 2021 Dec;28(12):3979-3989. Available from: doi: 10.1111/ene.15053
  3. Yan VK, Blais JE, Li X, Chui CS, Wei L, Yan BP, Knapp MR, Siu CW, Wong IC, Chan EW. Trends in cardiovascular medicine use in 65 middle-and high-income countries. Journal of the American College of Cardiology. 2021 Feb 23;77(7):1021-3.  
  4. Leung TY, Chan AY, Chan EW, Chan VK, Chui CS, Cowling BJ, Gao L, Ge MQ, Hung IF, Ip MS, Ip P. Short-and potential long-term adverse health outcomes of COVID-19: a rapid review. Emerging microbes & infections. 2020 Oct 7;9(1):2190-9. Available from: doi: 10.1080/22221751.2020.1825914
  5. Xiong XL, Wong KK, Chi SQ, Zhou AF, Tang JQ, Zhou LS, Chung PH, Chua G, Tung K, Wong I, Chui C. Comparative study of the clinical characteristics and epidemiological trend of 244 COVID-19 infected children with or without GI symptoms. Gut. 2021 Jan 7;70(2):436-8. Available from: doi: 10.1136/gutjnl-2020-321486
  6. Chui CS, Cowling BJ, Lim WW, Hui CK, Chan EW, Wong IC, Wu P. Patterns of inpatient antibiotic use among public hospitals in Hong Kong from 2000 to 2015. Drug safety. 2020 Mar 12; 43(6):595‐606. Available from: doi: 10.1007/s40264-020-00920-9
  7. Zhao J, Blais JE, Chui CS, Suh IH, Chen EY, Seto WK, Mok MT, Yan VK, Lau WC, Wong IC, Chan EW. Association Between Nonvitamin K Antagonist Oral Anticoagulants or Warfarin and Liver Injury: A Cohort Study. American Journal of Gastroenterology. 2020 Sep;115(9):1513-24. Available from: doi: 10.14309/ajg.0000000000000678 
  8. Cowling BJ, Chui CS, Lim WW, Wu P, Hui CK, Peiris JM, Chan EW. Use of influenza antivirals in patients hospitalized in Hong Kong, 2000-2015. Plos one. 2018 Jan 19;13(1):e0190306. Available from: doi: 10.1371/journal.pone.0190306
  9. Chui CS, Chan EW, Wong AY, Root A, Douglas IJ, Wong IC. Association between oral fluoroquinolones and seizures: a self-controlled case series study. Neurology. 2016 April 6;86(18):1708-15. Available from: doi: 10.1212/WNL.0000000000002633
  10. Wong AY, Wong IC, Chui CS, Lee EH, Chang WC, Chen EY, Leung WK, Chan EW. Association between acute neuropsychiatric events and Helicobacter pylori therapy containing clarithromycin. JAMA internal medicine. 2016 May 2;176(6):828-34. Available from: doi: 10.1001/jamainternmed.2016.1586
  11. Chui CS, Wong IC, Wong LY, Chan EW. Association between oral fluoroquinolone use and the development of retinal detachment: a systematic review and meta-analysis of observational studies. Journal of Antimicrobial Chemotherapy. 2015 Apr;70(4):971-8. Available from: doi: 10.1093/jac/dku507
  12. Chui CS, Man KK, Cheng CL, Chan EW, Lau WC, Cheng VC, Wong DS, Yang Kao YH, Wong IC. An investigation of the potential association between retinal detachment and oral fluoroquinolones: a self-controlled case series study. Journal of Antimicrobial Chemotherapy. 2014 Sep;69(9):2563-7. Available from: doi: 10.1093/jac/dku145

Journals: Psychological Medicine, British Journal of Clinical Pharmacology, PLoS One, Journal of Antimicrobial Chemotherapy, Hong Kong Journal of Paediatrics

2019/11-current Honorary Research Fellow, UCL School of Pharmacy, London, United Kingdom
2019/02-current Honorary Research Assistant, Department of Pharmacy, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China
2018/01-current Member, The University of Hong Kong Shenzhen Institute of Research and Innovation, Shenzhen, China
2018-current Convener and active member NeuroGEN (Neurological and Mental Health Global Epidemiology Network)
2015-16 Chair, Student Council, International Society for Pharmacoepidemiology
2014-15 Co-chair, Student Council, International Society for Pharmacoepidemiology
  • ASM Student and Postdoctoral Travel Award, ASM (American Society for Mcirobiology) Microbe, 2018
  • Outstanding Research Output Award, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 2017
  • John Snow Award (Best abstract submitted from a female research or a student living in a developing country), 32nd ICPE International Conference on Pharmacoepidemiology & Therapeutic Risk Management, 2016
  • Roche Postgrduate Research Student Prize, The University of Hong Kong, 2015
  • Rising Start Award, 9th Asian Conference on Pharmacoepidemiology, 2015
  • First Poster Prize, 14th Annual Meeting of the International Society of Pharmacovigilance, 2014
  • Best Presenter Award in Cardiovascular Issues and Antibiotics, 8th Asian Conference on Pharmacoepidemiology, 2013
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